The Sinister Six lineup in Spider-Man: No Way Home is missing one member, so who will the movie’s final villain be? The third installment of Sony and Marvel Studios’ Spider-Man franchise appears to be where a version of the Sinister Six will finally debut. Sony has had multiple ideas in the past to bring a collection of Spider-Man’s greatest villains together on the big screen. This included a Sinister Six movie as part of the Amazing Spider-Man franchise. While the Marvel Cinematic Universe reboot of Spider-Man scrapped those plans, it might be Spider-Man: No Way Home that brings the villainous team together.

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The first Spider-Man: No Way Home trailer confirmed that multiple villains will be featured in the movie. In an expected twist thanks to rumors and leaks, these villains will be from previous non-MCU Spider-Man movies. Sam Raimi and Tobey Maguire’s Spider-Man trilogy is represented with Willem Dafoe’s Green Goblin, Alfred Molina’s Doc Ock, and Thomas Hayden Church’s Sandman. The movie also includes Electro (Jamie Foxx) and Lizard (Rhys Ifans) from the Marc Webb and Andrew Garfield Amazing Spider-Man films. That only gives Spider-Man: No Way Home five villains, which is one short of the expected Sinister Six lineup.

Now that one of Spider-Man: No Way Home‘s possible Sinister Six villains is absent, that leaves a major question as to who will join the team. The most likely candidate based on the movie’s rumors is another villain from The Amazing Spider-Man 2. Paul Giamatti is reportedly returning to play Rhino in Spider-Man: No Way Home. Giamatti has denied these reports when he’s been asked, so there is a chance he won’t. It would be a nice piece of symmetry if Rhino was included, though, as it would give Spider-Man: No Way Home three villains from each of the previous Spider-Man franchises. And unless Dane Dehaan is brought back as Harry Osborn’s Green Goblin, the Amazing Spider-Man films don’t have another real option. Plus, Rhino’s return would point to every villain in Sinister Six originating through the multiverse.

There is a chance that Spider-Man: No Way Home could round out its Sinister Six team with someone that Holland’s Spider-Man already knows too. Vulture (Michael Keaton), Shocker (Bokeem Woodbine), and Scorpion (Michael Mando) are all still alive. Any of them could take part in the villain team-up, with Scorpion possibly the most likely of the three to participate since he desperately wanted to know who Spider-Man really was. Now that Peter’s identity has been outed, Scorpion could strike. It’s also worth considering that Jake Gyllenhaal’s Mysterio could join the Sinister Six instead. He appeared to have died in Spider-Man: Far From Home, but after teasing an origin connected to the multiverse, Spider-Man: No Way Home could actually make that true and include another version of him.

Due to the multiverse connections Spider-Man: No Way Home‘s current Sinister Six roster contains, it is also possible that Sony will use a character from Sony Spider-Man Universe. Tom Hardy’s Venom would be the biggest possible candidate to appear, while Jared Leto’s Morbius is also a contender. This might be unlikely as an appearance by either would surely build off their upcoming solo films, but both are not expected to release until after Spider-Man: No Way Home now. If Sony really wants to get creative, an appearance by Aaron Taylor-Johnson’s Kraven the Hunter could happen here. Kraven was long rumored to be in consideration to be one of the film’s main villains, but that appeared to change once the multiverse story was cracked.

In terms of which other Spider-Man villain has the best chance to be on the Sinister Six, the odds should be in Rhino or Scorpion’s favor most likely. Both could fit with what Spider-Man: No Way Home is doing, although Rhino’s multiverse connection might give him the edge between the two. Fans will know for sure when the movie finally comes out.

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